A Novel Mathematical Model to Predict the Severity of Postoperative Functional Reduction before Partial Nephrectomy: The Importance of Calculating Resected and Ischemic Volume

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Shin T.Y., Komninos C., Kim D.W., So K.S., Bang K.S., Jeong H.-J., Han W.K., Hong S.J., Jung B.H., Lim S.K., Lee S.K., Lee W.K., Rha K.H.

Journal of Urology 2014

Purpose: Preoperatively predicting postoperative kidney function is an essential step to achieve improved renal function and prevent chronic kidney disease. We introduce a novel formula especially to calculate resected and ischemic volume before partial nephrectomy. We examined whether resected and ischemic volume would have value for predicting postoperative renal function. Materials and Methods: We performed a retrospective cohort study in 210 patients who underwent robotic partial nephrectomy between September 2006 and October 2013 at a tertiary cancer care center. Based on abdominopelvic computerized tomography and magnetic resonance imaging we calculated resected and ischemic volume by the novel mathematical formula using integral calculus. We comparatively analyzed resected and ischemic volume, and current nephrometry systems to determine the degree of association and predictability regarding the severity of the postoperative functional reduction. Results: On multivariable analysis resected and ischemic volume showed a superior association with…(vermás)

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