Is Gleason Grade 5 Prostate Cancer Resistant to Conventional Androgen Deprivation Therapy?

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D’Amico A.V.

 

European Urology 2015

Synthesis of data from randomized trials suggests that long-term versus short-term androgen deprivation therapy may be most effective in men with Gleason grade 4 prostate cancer (PCa) and less or ineffective in men with Gleason grade 5 PCa.

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