Late recurrence after radical cystectomy: Patterns, risk factors and outcomes

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Linder B.J., Boorjian S.A., Hudolin T., Cheville J.C., Thapa P., Tarrell R.F., Frank I.

Journal of Urology 2014 191:5 (1256-1261)

Purpose We evaluate. The outcome in patients with late recurrence of urothelial carcinoma after radical cystectomy. Materials and Methods We identified 2,091 patients who underwent radical cystectomy at our institution between 1980 and 2006. Survival was estimated usin. The Kaplan-Meier method and compared based on recurrence timing (less than 5 years vs 5 or greater) and location (urothelial vs nonurothelial) usin. The log rank test. Cox proportional hazard regression models were used to evaluate variables associated with late recurrence and death from bladder cancer. Results Median postoperative followup was 16.6 years. Late recurrence was identified in 82 patients (3.9%). On multivariate analysis younger age (p = 0.0008), nonmuscle invasive disease (p = 0.01) and prostatic urethral involvement (p <0.0001) were significantly associated with…(vermás)


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