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To treat or not to treat, that is the question: the role of bone-targeted therapy in metastatic prostate cancer.

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Higano C.S.

Journal of clinical oncology: official journal of the American Society of Clinical Oncology 2014

The Oncology Grand Rounds series is designed to place original reports published in the Journal into clinical context. A case presentation is followed by a description of diagnostic and management challenges, a review of the relevant literature, and a summary of the authors’ suggested management approaches. The goal of this series is to help readers better understand how to apply the results of key studies, including those published in Journal of Clinical Oncology, to patients seen in their own clinical practice. A 62-year-old construction site manager experienced 6 weeks of back pain that was not responsive to over-the-counter nonsteroidal anti-inflammatory medications. He visited his wife’s primary care physician for evaluation. He denied neurologic symptoms or worsening of pain while lying down…(vermás)

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