A Systematic Review and Meta-analysis of Adjuvant and Neoadjuvant Chemotherapy for Upper Tract Urothelial Carcinoma

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Leow J.J., Martin-Doyle W., Fay A.P., Choueiri T.K., Chang S.L., Bellmunt J.

European Urology 2014

Context: The role of adjuvant chemotherapy (AC) or neoadjuvant chemotherapy (NC) remains poorly defined for the management of upper tract urothelial carcinoma (UTUC), although some studies suggest a benefit. Objective: To update the current evidence on the role of NC and AC for UTUC patients. Evidence acquisition: We searched for all studies investigating NC or AC for UTUC in Medline, Embase, the Cochrane Central Register of Controlled Trials, and abstracts from the American Society of Clinical Oncology meetings prior to February 2014. A systematic review and meta-analysis were performed…(ver más)


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