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Bacillus Calmette-Guérin failure in patients with non-muscle-invasive urothelial carcinoma of the bladder may be due to the urologist’s failure to detect urothelial carcinoma of the upper urinary tract and urethra

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Giannarini G., Birkhäuser F.D., Recker F., Thalmann G.N., Studer U.E.

European Urology 2014 65:4 (825-831)

Background Various reasons exist for so-called bacillus Calmette-Guérin (BCG) failure in patients with non-muscle-invasive urothelial bladder carcinoma (NMIBC). Objective To explore whether urothelial carcinoma of the upper urinary tract (UUT) and/or prostatic urethra may be a cause for BCG failure. Design, setting, and participants Retrospective analysis of 110 patients with high-risk NMIBC repeatedly treated with intravesical BCG, diagnosed with disease recurrence, and followed for a median time of 9.1 yr. Intervention Two or more intravesical BCG induction courses without maintenance… (ver más)

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